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Follicle Stimulating Hormone (FSH)

Product Specification:

FSH is a gonadotropin and a glycoprotein having two subunits. The alpha subunit is similar to those of LH, HCG, and TSH. The beta subunit is different from the other hormones and confers its biochemical specificity. FSH is secreted by the basophilic cells of the anterior pituitary. FSH stimulates the growth and maturation of the ovarian follicles in the female and stimulates spermatogenesis in the male.

General Information:

• Molecular Weight: 31,700 Daltons alpha-14,500 beta-17,200

• Source: Human pituitary extract

• IU/mg Standard grade 1,600 IU/mg

• IU/mg High purity 3,800 IU/mg

• Form: lyophilized powder

• Storage - 20 degrees C

• Stability: 5 years from date of manufacture

Method of Analysis:

• Purity is determined by SDS-Page.

• Acceptable level Standard grade: 50%

• Acceptable level High purity: 95%

Activity is determined by one of the following methods:

• Method DPC Immulite 1000
  Reference Preparation WHO 2nd IRP (78/549)

• Method ACS 180
  Reference Preparation WHO 2nd IS (94/632)

Contaminants Tested:

Contaminant	Method	Acceptable level; Standard Grade	Acceptable level; High Purity
TSH	ACS 180	Less than 1.5%	Less than 0.2%
LH	ACS 180	Less than 2%	Less than 0.2%
PRL	ACS 180	N/A	Less than 0.1%
GH	DPC Immulite 1000	N/A	Less than 0.1%