Key Scientific References
Meyers-Brown, GA, et al. (2010) Superovulation in Mares Using Recombinant Equine Follicle Stimulating Hormone: Ovulation Rates, Embryo Retrieval, and Hormone Profiles.
Jennings, MW, et al. (2009) The efficacy of recombinant equine follicle stimulating hormone (reFSH) to promote follicular growth in mares using a follicular suppression model.
Niswender, KD, et al. (2008) In vivo activity of recombinant equine follicle stimulating hormone in cycling mares. (Proceedings of the 7th Havemeyer International Symposium on Equine Embryo Transfer)
Roser, JF, et al. (2008) The embryo-to-ovulation ratio and hormone profiles in superovulated mares treated with recombinant equine FSH. (Proceedings of the 7th Havemeyer International Symposium on Equine Embryo Transfer)
Yoon, MJ, et al. (2007) The efficacy of a single chain recombinant equine luteinizing hormone (reLH) in mares: induction of ovulation, hormone profiles, and inter-ovulatory intervals.
Jablonka-Shariff , A, et al. (2007) Construction and Expression of an Ovine Single Chain Triple-domain Chimeric Gonadotropin: Tandem Linkage of the Genes Encoding the α- and FSHβ and LHβ subunits.
Jablonka-Shariff , A, et al. (2007) Expression and bioactivity of a single chain recombinant equine luteinizing hormone (reLH).
Niswender, KD, et al. (2007) In Vivo Activity of Recombinant Equine Follicle Stimulating Hormone in Cycling Mares. (The proceedings of the 53rd annual convention of the American Association of Equine Practitioners)
Niswender, KD, et al. (2006) Induction of Ovulation in the Mare with Recombinant Equine Luteinizing Hormone. (The proceedings of the 52nd annual convention of the American Association of Equine Practitioners)
These references are intended to provide information about the basic science and proof-of-concept for early versions of the products now being developed. The AAH therapeutic drugs are still in development.